Research Projects

The Surgery Clinical Trials Office (SurgCTO) supports the research activities for the Surgery Division clinical faculty at the University of Minnesota. SurgCTO is currently conducting approximately 45 clinical trials in various phases of enrollment and follow-up with a mix of investigator initiated, industry sponsored and government sponsored trails.

There are active clinical research trials in the following divisions:

  • Bariatric
  • Cardiothoracic
  • Solid Organ Transplant
  • Vascular

We also provide support for Humanitarian Use Devices (HUDs).

Bariatric

Bariatric

  • Factors Impacting Healthcare Utilization
  • Paraesophageal Hernia Repair

For additional information about the below trial(s) please contact surgcto@umn.edu or 612-624-7463.

  • ADA - Bariatric Surgery and Adipose Inflammation Dysfunction and Type 2 Diabetes Mellitus
  • ReCharge PAS - The Safety and Efficacy of vBloc Therapy Delivered by the Maestro Rechargeable System for the Treatment of Obesity

Cardiothoracic

Cardiothoracic

For additional information about the below trial(s) please contact surgcto@umn.edu or 612-624-7463.

  • EXPAND Heart - International Trial to Evaluate the Safety and Effectiveness of The Portable Organ Care System (OCS™) Heart For Preserving and Assessing Expanded Criteria Donor Hearts for Transplantation
  • EXPAND Lung - International Trial to Evaluate the Safety and Effectiveness of The Portable Organ Care System (OCS™) Lung For Recruiting, Preserving and Assessing Expanded Criteria Donor Lungs for Transplantation
  • HeartWare PAS - Post- Approval Study on Patients Who Received a HeartWare HVAD® During IDE Trials
  • Intermacs - Interagency Registry for Mechanically Assisted Circulatory Support
  • MOMENTUM CAP - Study of MagLev Technology in Patients Undergoing MCS Therapy With HeartMate 3™ Continued Access Protocol
  • Pedimacs - Pedimacs is the pediatric portion of Intermacs
  • SUSTAIN-IT - Sustaining Quality of Life of the Aged: Heart Transplant or Mechanical Support

Solid Organ Transplant

Solid Organ Transplant

  • Decision Aid
  • Donor Long-Term Follow Up
  • Microbiome in Kidney Transplantation
  • Patient Center Report Card

For additional information about the below trial(s) please contact surgcto@umn.edu or 612-624-7463.

  • ASTOUND - To Compare the Effects of Immediate-Release Tacrolimus and Astagraf XL on Donor-Specific Antibody Formation and the Development of Immune Activation in de Novo Kidney Transplant Recipients
  • BEST - Belatacept Early Steroid Withdrawal Trial
  • CONNEKT (Shire AMR) -  Study to Evaluate the Efficacy and Safety of Cinryze® for the Treatment of Acute Antibody-Mediated Rejection in Patients with Kidney Transplant
  • DART - Non Invasive Blood Test To Diagnose Acute Rejection After Kidney Transplantation
  • DeKAF - A Study of Factors That Affect Long-Term Kidney Transplant Function
  • ENLIST - Evaluating Nulojix (Belatacept) Long-Term Safety in Transplant
  • Everolimus Living Liver / H2307 - Efficacy and Safety of Everolimus in Liver Transplant Recipients of Living Donor Liver Transplants
  • HOPE Act - Observational Study of Solid Organ Transplantation Utilizing HIV-Positive Donors in HIV-Positive Recipients
  • Liver PROTECT - TransMedics (OCS) Liver Trial: Preserving and Assessing Donor Livers for Transplantation
  • ValA vs ValG - ValGanciclovir Versus ValAcyclovir for Viral Prophylaxis in Kidney Transplantation

Vascular

Vascular

For additional information about the below trial(s) please contact surgcto@umn.edu or 612-624-7463.

  • Valiant Evo - Valiant Evo US Clinical Trial
    Closed to Enrollment
  • Low Dose - Development of Ultra-Low Dose CT Based Screening for Aortic Aneurysms
    Open to Enrollment 
  • RelayPro - Study of the RelayPro Thoracic Stent-Graft in Subjects with an Acute, Complicated Type B Aortic Dissection
    Open to Enrollment 

Humanitarian Use Device (HUD)

Humanitarian Use Device (HUD)

For additional information about the below trial(s) please contact surgcto@umn.edu or 612-624-7463.

  • Enterra - HDE (Human Device Exemption) Enterra Therapy Gastric Stimulation
    Open to Enrollment